Although cannabis is the most widely used illicit substance in the world, resulting sexual dysfunction is largely ignored. And for a while, “it is known, in fact, the negative impact on the sexual sphere of the active ingredient of cannabis (THC) and how regular cannabis use has a strong impact on the sexual health of users , men and women (AMA Smith et al., 2010).
erectile dysfunction (ED)
A recent review of the scientific literature shows that cannabis can cause erectile dysfunction males. Cannabis.One of the most consumed substances is also there, and is generally less falsely regarded as one of the harmful effects. Studies on the use of cannabis has shown very clearly how this substance with certain receptors in the brain interacts, and recent studies have shown that these receptors are also present in the penis. In particular, both the analysis of animal studies, in vitro, erectile function device antagonist resulting from stimulation of specific receptors in the cavernous tissue of the penis, cannabis while there is a correlation between the disorder and cannabis sexual stress (Shamloul R et al, 2011).
Inhibition of orgasm
Marijuana use has also been associated with inhibition of orgasm in the connection. This is the result of a study conducted by the University of St. Louis, Missouri (USA), 3004, under the direction of drug users who have evaluated the relationship between drug use and sexual dysfunction. The study found that orgasm was inhibited by the use of marijuana and alcohol, had painful intercourse with the use of marijuana and other drugs, as well as the inhibition of sexual arousal (SD Johnson et al, 2004). Another survey of La Trobe University in Melbourne, Australia, through telephone interviews, involved almost 8,700 volunteers aged between 16 and 64 years. Cannabis accounted interview last year about 9% of the sample; This 1.5% consumption daily, 1.5% more per week, 5.8% occasional use. The results of the study showed that daily cannabis use is associated with sexual dysfunction likely double compared to those who do not consume, and that these consequences were men and women are subjected. In addition, women have had the chance to sexually transmitted diseases has increased 7 times the contract with nonusers; This effect was not observed in men, but they were 4 times more difficulty reaching orgasm, or the ability to 2 times higher rank or a too fast or too slow (AM Smith et al. 2010 ).
The abuse of cannabinoids can help cause of infertility in humans. This was done by the Italian Vergata University study confirmed Tor (2009) New perspectives for understanding the phenomena of oligospermia or opening azoospermia (complete absence or drastic reduction in sperm count, often with reduced motility ), especially in patients with normal known structure of chromosomes and the absence of genetic defects or occlusive included diseases.Research first, as in mice, the endocannabinoid system (which also acts as marijuana) is the process thus shown to contribute to spermatogenesis, to cause infertility (P Grimaldi et al, 2009).
Low impact sperm fertilizing ability
Murphy (2001) showed that cannabis use in humans reduces blood levels of three hormones LH, FSH and testosterone. Through his research, he was also found in cannabis smokers than nonsmokers, a lower incidence of competent sperm that can fertilize.
Abnormalities decreased testosterone, spermatogenesis and sperm
The main negative impact on the consumption of human cannabis in men and women in the reproductive system are: for male fertility, as a decrease in serum LH and testosterone, inducing gynecomastia, decreased spermatogenesis and mobility (oligospermia), and induction of sperm acrosome reaction block anomalies (Murphy, 2001).
Increase testosterone, abnormal menstrual cycle, premature birth
For female fertility, the main negative effects on the reproductive system are: changes in LH levels, increases the inhibition of secretion of prolactin, testosterone levels, changes in menstrual periods, poor women Recovery oocyte undergoing in vitro fertilization, fetal malformation growth, increased incidence of premature births, premature births and low birth weight of the fetus, difficulties at work (N Battista et al, 2008; Park B et al, 2004).
- Battista N, N Pasquariello, Di Tommaso M Maccarrone M. (2008), the interaction between endocannabinoids, steroids and cytokines in the control of human reproduction. Journal of Neuroendocrinology, 20: 82-89. doi: 10.1111 / j.1365-2826.2008.01684.x
- Grimaldi P, P Orlando, Di Siena S, M Lolicato, Petrosino S, T Need, Jeremiah R De Petro Cellis L, V. Di Marzo The endocannabinoid system and the central role of CB2 receptors in mouse spermatogenesis. USA Proc Natl Acad Sci A. 7. July 2009; 106 (27): 11131-6.
- Johnson SD, Phelps DL, Cottler LB. The association of sexual dysfunction and substance in a sample of the epidemiological community. Arch Sex Behav. February 2004; 33 (1): 55-63.
- endocrine Murpy L .. In: Grotenhermen (Editor): Cannabis and cannabinoids. Pharmacology, toxicology and therapeutic potential. Huber 2001a Bern
- Park B McPartland JM, Mr. Glass cannabis, cannabinoids and reproduction. prostaglandin fatty acids Leukot Essent. February 2004; 70 (2): 189-97.
- Smith WADA Ferris YES, Simpson JM, Shelley J, M Pitts, J. Richter and cannabis use and sexual health. J Sex Med 2010; 7: 787-793.
- Shamloul R AJ Bella, the effects of cannabis on Male Sexual Health, Journal of Sexual Medicine 2011, Volume 8, Number 4, 971-975 pages.