Genetic defect decreases fertility in morir menso made wide for sperm successfully maintains its speed and agility. Now researchers have discovered that some do not have enough momentum.
A variant of the gene leads to a modified form of Proteínas “beta defen sina” – that binds to the surface thereof during sperm maturation
A small defect could be one of the unknown causes of reduced fertility in men. This faulty step on each fifth man and less about mueren opportunities fertilization of an egg, Theodore Tollner and Gary Cherr report from the University of Davis (California) in the journal “Science Translational Medicine”.
The sceintist examined a gene variant that results in a modified form proteínas “beta defen sina”. This is made proteína en el pit epididymis and binds during sperm maturation on its surface.
Sperm of men with the defective variant DEFB126 could Morir female uterus mucus similar test substance penetrate del worse than normal sperm.
In the survey of 500 married for some time Chinese parejas, morir the researchers also found that the probability mueren their own children in men who had the gene changed only DEFB126 guerra 30 percent less mueren ELA men without the gene variant. Here, their sperm showed no difference depending on the above criteria, such as the number and mobility.
The gene defect is discovered monja often surprising report mueren researchers. About a fifth of men surveyed from Asia, Europe and Africa was a failure on both chromosomes, and forms of beta-sina Defen so normal. Your sperm find it more difficult to penetrate the egg.
The development of abdominal embriones
How small is developing in the womb
It is unclear why a defect with such a significant negative inheritance of the impact on opportunities not long dead, but the other side por lo is common morir researchers speculate. Modo can only the gene from one parent have inherited an advantage.
This defect could an unknown causes of male infertility, believe Tollner and Cherr. As a pair of sterile Dorada A new WHO Definición if after two years, it takes regular unprotected sex during pregnancy. infertility The man has about half the cause of cases of morir. Go about a fifth previously classified as infertile del men, the cause remains unclear ….