Neurocure focuses on diseases, neuroinflammation and function of cerebrovascular disorders network structures, the prototypical disease stroke and multiple sclerosis and epilepsy and CNS focal by mitochondrial dysfunction. The neurological disorders share a variety of disease mechanisms, therefore, it is expected that the joint exploration of new synergies in therapy. Cerebrovascular disease (stroke) neuroinflammation (eg multiple sclerosis) brain development disorders (eg epilepsy)
MS [disseminated encephalomyelitis also]
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. In a great number of inflammation in the brain and spinal cord myelin sheaths of axons are degraded by immune cells in the body. Because the myelin sheaths are used for electrically insulating the axons and are necessary for the transmission of electrical impulses. Therefore, the loss of the myelin sheath causes various neurological disorders in the intensity and location dependent inflammation. The cause of multiple sclerosis is far unresolved. to define the geographic differences in the incidence, the involvement of environmental factors is discarded. In addition, immune system disorders, infections and genetic causes are described, but not enough, can be widely supported. Frequency (epidemiology) Multiple sclerosis is next to epilepsy one the most common neurological disease in young adults. The incidence of the disease differently depending on geographic location, the frequency increases with distance from the equator. In Germany, about 120,000 people affected by multiple sclerosis. Worldwide the number of MS patients is estimated at 2.5 million people. Women are more likely than men in general. Symptoms Depending on where the inflammation in the central nervous system are multiple sclerosis causes almost contained no neurological symptoms. Often, but not specific, visual disturbances, sensory disturbances, incoordination, speech and paralysis drawled. The management of multiple sclerosis, there is still no cure. Drugs and physical therapy, the progression of the disease, however, can reduce the speed and intensity of the symptoms can be reduced. be used for symptom relief, anti-inflammatory drugs (eg. glucocorticoids) and painkillers. the progression of the disease are used to delay the drug to suppress modulate the immune system (immunosuppressant) or. Very often complementary therapy exercises to reduce muscle weakness, joint stiffness and paralysis (z. B. riding, water sports, autogenous training, yoga)
If a disease described epilepsy, characterized by spontaneous seizures.
The so-called epileptic seizure is caused by the synchronous firing of groups of neurons in the brain, to be a sudden and involuntary spasms and muscle disorders. Causes Epilepsy can have several causes. In addition to malformations of the brain tissue brain injuries are caused by a lack of oxygen at birth, brain tumors and head injuries are caused to causes. But the brain (encephalitis), metabolic disorders and alcohol, infections of the abuse of drugs and substances can trigger epilepsy. However, there are also forms of epilepsy, its causes far unresolved. Frequency (epidemiology), although about 5% of all people in life after suffering a seizure strategy only 0.5 to 1% of the active population of epilepsy (seizures) known regular. In Germany it is about 400,000 to 800,000 people. The number of new cases per year is highly dependent on age. Although difficult to 90 of 100,000 children a year from epilepsy is the number of new cases per 100,000 adults 20 In elderly patients (60 years) is the number of new cases increases again to 60 per 100,000. The occurrence of seizures or simple febrile seizures in children are not included in these figures. Symptoms of epilepsy is fundamentally different in both partial and generalized forms. In areas of partial seizures cortex limited by the synchronized firing of the affected neurons. Symptoms are limited depending on the location of the affected area to specific body regions. In partial seizures and secondarily generalized seizures, however, you can enter. generalized seizures involve the whole brain or large areas of both hemispheres simultaneously. Therefore, the seizure also affects the entire body. In addition to reporting the involuntary muscle spasms and affected altered consciousness and sensitivity to unconsciousness stereotyped movements. Many attacks are linked to the area affected by a vague feeling that the person called will. Treatment of epilepsy can be treated with drugs, depending on the form and severity. Antiepileptic drugs should be about 2/3 of the patients to live a nearly got free life can be avoided. In particularly serious cases, therapies and nondrug carried propose certain requirements may even be an operation.