The current definition of leukoplakia, also shared by the Collaborating Centre for Oral and precancerous cancer World Health Organization, is a white lesion of the oral mucosa, which can not be clinically associated or pathologically with another disease process . Implicitly, that this type of injury is a potential cancer risk and therefore requires careful monitoring clinical and histological. Histologically aleukoplakia appears only as a squamous epithelial hyperplasia with hyperkeratosis and / or paraqueratosis, with differences related to different ways. Since the risk of malignant transformation is concerned, the literature provides a large pair of scissors, quantifiable in a range of 0.13% to 17.5%. In this regard the warty proliferative leukoplakia is a subcategory in heterogeneous forms and therefore more susceptible to malignant clays. It therefore seems essential for the clinic, which as you can see, often face conditions of this type in the characters keep the injury or the basis for determining at least to induce a clinical suspicion.
This refers to the causal aspects, the PVL is no particular reason, risk factors, and comparison with those of leukoplakia town provides against indications. The authors declare that there is no correlation with risk factors, paradoxically, it is one of the most revealing aspects of PVL. Other epidemiological interest data is most common in women and people over 60 years.
More complex considerations of disease progression. The first clinical presentation of focal type, this important aspect, the warty leukoplakia often way belated recognition. The topographic measurement below the lesion led more irregular appearance pathognomonic. The lesions are usually initially to get the margins described and can be found in the buccal mucosa and into multiple sites in language frequently. great attention to appearance multifocal lesions was given, noting that squamous cell carcinoma of the histological tumor carcinogenesis phenomenon of the oral cavity typecharacterized field.
Regarding differential diagnosis, some authors say the pathologies that can take over as a phenomenon, to the point that at times differ only by the histopathological level, warty hyperplasia, hairy leukoplakia Cell and some forms of lichen.
Finally, they want to make a referral to treatment, there are several surgical therapies, and not, as none of them will be respected of the radical efficiency starts. A previous article refers to the use, the laser is now consolidated in this area. Usually, such cases usually turn specialized referral centers, where they receive clinical follow-up and multidisciplinary treatment approach.